Playing with my new macro extension tube for my camera ( some photos to upload as soon as I get some time!), I have had to focus manually as there is no controls passed through to the lens. In the end I have found it easiest to set the focus to infinity and adjust either the zoom or the position on the object to get the best focus. What it has shown me is that the viewfinder is quite small, which I had not had a problem with up till now, and also it it quite difficult to focus.
Back in the day my old Pentax film camera had a manual focus and to help with that it had a bit in the middle of the viewfinder that split the image slightly so that you could tell that if the image was lined up correctly it was also in focus. Really simple and quick to get the correct focus.
I am also getting used to how much my tripod flexes when I have adjusted it to the right place. With the weight of the 70-200mm lens and the extender the end of the lens drops by just a little after I have set it using the tripod and when you take into account this is macro that can make quite a difference. It's quite a skill to set the tripod a little higher and let the lens fall to the correct place but I am getting better. That and moving the subject can be simpler!